Pupillary reflexes in complex regional pain syndrome: asymmetry to arousal stimuli suggests an ipsilateral locus coeruleus deficit

In complex regional pain syndrome (CRPS), the initial response to limb injury evolves into an intractably painful condition associated with sensory, autonomic, motor and trophic disturbances 5,41. Sensory disturbances often encompass much of the body, particularly on the affected side 10-12,15,39, possibly due to central sensitization and/or failure of inhibitory pain controls.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Original Reports Source Type: research