Use of Deep-Learning Genomics to Discriminate Healthy Individuals from Those with Alzheimer's Disease or Mild Cognitive Impairment

CONCLUSION: The DLG model can achieve higher accuracy and sensitivity when applied to progression of AD. More importantly, we discovered several novel genetic biomarkers of AD progression, including rs6311 and rs6313 in HTR2A, rs1354269 in NAV2, and rs690705 in RFC3. The roles of these novel loci in AD should be explored in future research.PMID:34336000 | PMC:PMC8298161 | DOI:10.1155/2021/3359103
Source: Behavioural Neurology - Category: Neurology Authors: Source Type: research