HER2 overexpression is a putative diagnostic and prognostic biomarker for late-stage colorectal cancer in North African patients

Conclusion: To our knowledge, this is the first study that HER2 overexpression correlates with more aggressive colorectal cancer in North African population. Our study shows that HER2 overexpression associates with right colon surgeries. Also, the correlation of mRNA and protein expression could warrant the implementation of a nationwide screening program for HER2 positivity in CRC patients. Taken together, stratifying patients according to HER2 expression can help in the diagnosis and prognosis of CRC patients from North African origin.PMID:34319852 | DOI:10.1080/19932820.2021.1955462

Source: Libyan Journal of Medicine - July 28, 2021 Category: General Medicine Authors: Eman A Abdul Razzaq Thenmozhi Venkatachalam Khuloud Bajbouj Mohamed Rahmani Amena Mahdami Surendra Rawat Naziha Mansuri Hussein Alhashemi Rifat Akram Hamoudi Riyad Bendardaf Source Type: research