Cardiac arrhythmias six months following traumatic spinal cord injury

J Spinal Cord Med. 2021 Jul 22:1-7. doi: 10.1080/10790268.2021.1950453. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the incidence of cardiac arrhythmias at six months following traumatic spinal cord injury (SCI) and to compare the prevalence of arrhythmias between participants with cervical and thoracic SCI.DESIGN: A prospective observational study using continuous twenty-four-hour Holter monitoring.SETTING: Inpatient rehabilitation unit of a university research hospital and patient home setting.PARTICIPANTS: Fifty-five participants with acute traumatic SCI were prospectively included. For each participant, the SCI was characterized according to the International Standards for Neurological Classification of SCI by the neurological level and severity according to the American Spinal Injury Association Impairment Scale.OUTCOME MEASURES: Comparisons between demographic characteristics and arrhythmogenic occurrences as early as possible after SCI (4 ± 2 days) followed by 1, 2, 3, 4 weeks and 6 month time points of Holter monitoring.RESULTS: Bradycardia (heart rate [HR]
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Authors: Source Type: research

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Auton Neurosci. 2021 Aug 10;235:102867. doi: 10.1016/j.autneu.2021.102867. Online ahead of print.ABSTRACTInjury to descending autonomic (sympathetic) pathways is common after high-level spinal cord injury (SCI) and associated with abnormal blood pressure and heart rate regulation. In individuals with high-level SCI, abnormal sympathovagal balance (such as during autonomic dysreflexia; paroxysmal hypertension provoked by sensory stimuli below the injury) is proarrhythmogenic. Exercise training is a key component of SCI rehabilitation and management of cardiovascular disease risk, but it is unclear whether exercise training ...
Source: Autonomic Neuroscience - Category: Neuroscience Authors: Source Type: research
J Spinal Cord Med. 2021 Jul 22:1-7. doi: 10.1080/10790268.2021.1950453. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the incidence of cardiac arrhythmias at six months following traumatic spinal cord injury (SCI) and to compare the prevalence of arrhythmias between participants with cervical and thoracic SCI.DESIGN: A prospective observational study using continuous twenty-four-hour Holter monitoring.SETTING: Inpatient rehabilitation unit of a university research hospital and patient home setting.PARTICIPANTS: Fifty-five participants with acute traumatic SCI were prospectively included. For each participant, the...
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Authors: Source Type: research
Conclusion/Clinical Relevance: The case demonstrated that refractory AD could be managed with ITB in an emergency. PMID: 31815605 [PubMed - as supplied by publisher]
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research
The year 2018 is nearly over, and it is time for us to reveal what we believe were the most notable developments in medical technology. We considered a technology’s clinical importance, the greatness of the leap that it’s making over exis...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Medicine Society Surgery Source Type: blogs
Authors: Varani K, Vincenzi F, Merighi S, Gessi S, Borea PA Abstract Adenosine, the purine nucleoside, mediates its effects through activation of four G-protein coupled adenosine receptors (ARs) named as A1, A2A, A2B and A3. In particular, A1ARs are distributed through the body, primarily inhibitory in the regulation of adenylyl cyclase activity and able to reduce the cyclic AMP levels. Considerable advances have been made in the pharmacological and molecular characterization of A1ARs, which had been proposed as targets for the discovery and drug design of antagonists, agonists and allosteric enhancers. Several lin...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
The year 2016 presented the world with a number of big surprises. Some positive, some negative, depending on whom one asks. Here at Medgadget, 2016 will be remembered for many amazing and pleasantly unexpected medical technology developments, many of...
Source: Medgadget - Category: Medical Equipment Authors: Tags: Exclusive Source Type: blogs
Alzheimer's disease (AD) is a leading cause of death and disability among older adults. Modifiable vascular risk factors for AD (VRF) include obesity, hypertension, type 2 diabetes mellitus, sleep apnea, and metabolic syndrome. Here, interactions between cerebrovascular function and development of AD are reviewed, as are interventions to improve cerebral blood flow and reduce VRF. Atherosclerosis and small vessel cerebral disease impair metabolic regulation of cerebral blood flow and, along with microvascular rarefaction and altered trans-capillary exchange, create conditions favoring AD development. Although currently the...
Source: Experimental Biology and Medicine - Category: Research Authors: Tags: Physiology Source Type: research
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