Inflammatory bowel disease as a risk factor for premature coronary artery disease.
CONCLUSION: Most of the clinical sequelae of CV disease events are the result of inflammatory changes at the vascular level. While IBD is associated with a chronic inflammatory state as reflected by high sedimentation rates, C-reactive protein (CRP), homocysteine levels, etc., our data seem to indicate that chronic inflammation in the absence of traditional risk factors is not associated with an increased risk of premature CV disease events. More wide-scale prospective studies should be performed to elucidate the relationship, if any, between chronic inflammation and CV disease risk.
PMID: 25699123 [PubMed]
Source: Clin Med Res - Category: Research Authors: Ruisi P, Makaryus JN, Ruisi M, Makaryus AN Tags: J Clin Med Res Source Type: research
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