In the article, “Nutritional Management for Dogs and Cats with Chronic Kidney Disease,” by Valerie J. Parker, published in the May 2021 issue (Volume 51, number 3, pages 685-710), in Table 3 on page 12, for the “2020 AAFCO Feline adult maintenance maximum requirement” under the “Vitamin D (IU)”, the co rrect number should be 752 instead of 75.2.
Source: Veterinary Clinics of North America: Small Animal Practice - Category: Veterinary Research Source Type: research

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This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clínico–La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D i...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionClinical manifestations ranged from cases of neonatal demise to those diagnosed in adulthood. The minigene assay results indicate the importance of functional analysis, and call into question the fundamental belief that at least one non-truncating mutation is necessary for perinatal survival.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
AbstractChronic kidney disease (CKD) is associated with distinct alterations in mineral metabolism in children and adults resulting in multiple organ dysfunctions. Children with advanced CKD often suffer from impaired bone mineralization, bone deformities and fractures, growth failure, muscle weakness, and vascular and soft tissue calcification, a complex which was recently termed CKD-mineral and bone disorder (CKD-MBD). The latter is a major contributor to the enhanced cardiovascular disease comorbidity and mortality in these patients. Elevated circulating levels of the endocrine-acting phosphaturic hormone fibroblast gro...
Source: Molecular and Cellular Pediatrics - Category: Cytology Source Type: research
Condition:   Non-diabetic Chronic Kidney Disease Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo Sponsor:   Bayer Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This study aimed to validate the available SCr-based eGFR equations in comparison with a measured (mGFR), stratified by chronic kidney disease (CKD) stage and age at the time of testing.MethodsOne hundred twenty-seven pediatric kidney transplant recipients with 411 mGFR values (plasma clearance of iothalamate) were enrolled in this retrospective study. The bias, precision, and accuracy (percentage of estimates within 10% and 30% of mGFR) of five SCr eGFR equations (original Schwartz, CKiDSCr equation, Pottel, Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)) were...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
AbstractThe risk of tuberculosis (TB) disease is increased in children with chronic kidney disease (CKD), even higher in stage 5 CKD/kidney failure and especially high after kidney transplantation due to immunosuppression. TB disease may follow recent primary infection, or result from reactivation of latent infection. Reactivation is more common in adults, while progression following primary infection makes up a greater proportion of disease in children. Recommendations for preventing TB disease in some low TB incidence countries have previously included offering Bacillus Calmette-Gu érin (BCG) vaccine to all childr...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionOur study provides further insight into factors potentially associated with erythropoiesis in pediatric kidney transplant recipients.Graphical abstractA higher resolution version of the Graphical abstract is available as Supplementary information
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
AbstractBackgroundNephritis is a recognised complication of IgA vasculitis (IgAV, Henoch-Sch önlein purpura) contributing to 1–2% of all chronic kidney disease (CKD) stage 5. Improved understanding may reduce irreversible damage in IgAV nephritis (IgAV-N).ObjectiveThe aim of this study was to perform a comprehensive systematic literature review to identify promising clinical and pre-clinical urine biomarkers in children with IgAV-N that could predict the presence of nephritis and/or determine its severity.MethodsA systematic literature review was performed using four search engines and a predefined search term s...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
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