Editorial: The National COVID Cohort Collaborative Consortium Combines Population Data with Machine Learning to Evaluate and Predict Risk Factors for the Severity of COVID-19

Med Sci Monit. 2021 Aug 2;27:e934171. doi: 10.12659/MSM.934171.ABSTRACTInfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) commonly presents with pneumonia. However, COVID-19 is now recognized to involve multiple organ systems with varying severity and duration. In July 2021, the findings from a retrospective population study from the National COVID Cohort Collaborative (N3C) Consortium were published that included analysis by machine learning methods of 174,568 adults with SARS-CoV-2 infection from 34 medical centers in the US. The study stratified patients for COVID-19 according to the World Health Organization (WHO) Clinical Progression Scale (CPS). Severe clinical outcomes were identified as the requirement for invasive ventilatory support, or extracorporeal membrane oxygenation (ECMO), and patient mortality. Machine learning analysis showed that the factor most strongly associated with severity of clinical course in patients with COVID-19 was pH. A separate multivariable logistic regression model showed that independent factors associated with more severe clinical outcomes included age, dementia, male gender, liver disease, and obesity. This Editorial aims to present the rationale and findings of the largest population cohort of adult patients with COVID-19 to date and highlights the importance of using large population studies with sophisticated analytical methods, including machine learning.PMID:34...
Source: Medical Science Monitor - Category: Research Authors: Source Type: research

Related Links:

PlastCare Offers FDA Approved Dental Supplies on bttn. PlatformSEATTLE, Sept. 21, 2021 /PRNewswire/ -- bttn., a HealthTech startup providing a B2B e-commerce platform for purchasing medical supplies, today announced a massive expansion to its product catalog with the addition of 93 PlastCare USA products for dental practitioners. bttn. has seen a dramatic increase in the number of dental practices utilizing its medical supply platform in recent months. The addition of the PlastCare catalog fleshes out bttn.'s dental supply offerings and brings 23 new dental product categories to customers of the rapidly grow...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
A low number of children have contracted Covid-19 in Oregon compared with other states, according to Oregon Health&Science University ’s latest forecast. Only seven states have lower pediatric census rates than Oregon, where 0.70 per 100,000 of those under the age of 18 are hospitalized for Covid, according to the report, from Peter Graven, lead data scientist in OHSU’s Business Intelligence unit. Graven said that the data s uggest that children are protected when the adults around them are…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
While the Covid-19 vaccines were developed far from Pittsburgh, a lab at Carnegie Mellon University is making advances in the delivery of the same type of messenger RNA technology that made the first vaccines possible to battle other diseases. The second day of the Precision Medicine World Conference, held in downtown Pittsburgh, began with examples of how the Covid-19 pandemic had changed the region and the world — and BioNTech founders Ugur Sahin and Ozlem Tureci and a leading mRNA researcher…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Sep 28, 2021. . Sponsored by Centers for Disease Control and Prevention
Source: Rural events via the Rural Assistance Center - Category: Rural Health Source Type: events
Studies suggesting ivermectin is an effective Covid treatment relied on evidence ‘that has substantially evaporated under close scrutiny’, fresh research showsFollow the Australia coronavirus blogCovid vaccine rollout and rates tracker; Cases, trends and data trackerGet our free news app;get our morning email briefingDr Carlos Chaccour ran into difficulty when he and his colleaguesbegan recruiting patients in Peru for their study to determine the effect of a daily dose of the anti-parasitic drug ivermectin on people infected with Covid-19.“We would call the patient and say, ‘You have just been diagn...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Coronavirus Medical research Australia news Source Type: news
At least three promising antiviral treatments for COVID-19 are being tested in clinical trials, with results expected as soon as late fall or winter.Kaiser Health News
Source: Medscape Pediatrics Headlines - Category: Pediatrics Tags: Infectious Diseases News Source Type: news
Gov. Jim Justice is asking why the daily tolls don't motivate more people to get their COVID-19 shots.Associated Press
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
[Nation] The government has banned Mashujaa Day celebrations in all counties due to the Covid-19 pandemic.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[WHO] I was greatly heartened by the global show of support demonstrated at the Global COVID-19 Summit hosted by the President of the United States of America, Joe Biden, on Wednesday, 22 September 2021.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Med Sci Monit. 2021 Aug 2;27:e934171. doi: 10.12659/MSM.934171.ABSTRACTInfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) commonly presents with pneumonia. However, COVID-19 is now recognized to involve multiple organ systems with varying severity and duration. In July 2021, the findings from a retrospective population study from the National COVID Cohort Collaborative (N3C) Consortium were published that included analysis by machine learning methods of 174,568 adults with SARS-CoV-2 infection from 34 medical centers in the US. The study stratified pa...
Source: Medical Science Monitor - Category: Research Authors: Source Type: research
More News: Biomedical Science | Coronavirus | COVID-19 | Dementia | Eating Disorders & Weight Management | International Medicine & Public Health | Learning | Liver | Liver Disease | Obesity | Pneumonia | Research | Respiratory Medicine | SARS | Science | Study | Universities & Medical Training | Urology & Nephrology | WHO