Clinical Features of Acute Chikungunya Virus Infection in Children and Adults during an Outbreak in the Maldives

We describe the genotype and polymorphism of Maldives chikungunya virus using phylogenetic analysis. All isolates were consistent with the East Central South African genotype of the Indian Ocean lineage, with a specific E1-K211E mutation. In addition, we explored the clinical and laboratory manifestations of acute chikungunya in children and adults, of which severe infection was found in some children, whereas arthritis primarily occurred in adults. Arthritides in adults occurred irrespective of underlying comorbidities and were associated with the degree of viremia.PMID:34339379 | DOI:10.4269/ajtmh.21-0189

Source: Am J Trop Med Hyg - August 2, 2021 Category: Infectious Diseases Authors: Hisham Ahmed Imad Juthamas Phadungsombat Emi E Nakayama Keita Suzuki Ahmed Mifthah Ibrahim Aminath Afaa Aminath Azeema Aminath Nazfa Aminath Yazfa Anoosha Ahmed Athifa Saeed Azna Waheed Fathimath Shareef Mohamed Moinul Islam Shausha Mohamed Anees Sana Sal Source Type: research