Text-message ‘nudges’ can encourage holdouts to get COVID vaccination, study finds

New UCLA-led research indicates that simple text messages emphasizing the easy availability of COVID-19 vaccines successfully boosted the number of people who got the shot.The researchers, from theDavid Geffen School of Medicine at UCLA, theUCLA Anderson School of Management and Carnegie Mellon University, say their findings held true across all demographics, including groups that have been hesitant to receive the vaccine.“We found that text messages that stressed the accessibility of the vaccine and that included ‘ownership’ language — such as ‘The vaccine has just been made available for you’ and ‘Claim your dose today’ — significantly increased vaccine uptake,” said senior study author Dr. Dani el Croymans, a primary care physician and medical director of quality at UCLA Health.For the study,published today in the peer-reviewed journal Nature, the researchers analyzed data from two randomized, controlled trials conducted with UCLA Health patients, most over the age of 65, who were eligible for the COVID-19 vaccine in January and February 2021.In the first trial, about 93,000 participants who had initially been notified byemail, regular mail or phone of their eligibility for the vaccine either did not receive a follow-up text or received one of four types of messages: a simple text reminder, a reminder that included an informationalvideo, a reminder with the above-mentioned ownership language, or a reminder with bo...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Over the past years, smart algorithm-powered, text- or voice-based interfaces have multiplied, and they are also taking their place in healthcare. The Medical Futurist believes Molly, Ginger, Replika and the others will ease the burden on doctors in primary care and help patients learn to take care of their health responsibly. Would you like to try one? Check out the following video about healthcare chatbots: The age of talking algorithms is here In 2018, Google stunned the world with the latest feature of the Google Assistant, Duplex, which was able to make an appointment in a hair salon in eerily hum...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design AI chatbot digital health Innovation List medical Personalized medicine technology chatbots health chatbot Source Type: blogs
Items regarding COVID-19 information are indicated with an * In the Dragonfly: *NNLM Covid-19 Symposium. Keynote Speakers Announced. Registration is Open The Network of the National Library of Medicine (NNLM) is excited to announce a new, free virtual symposium focused on addressing the COVID-19 infodemic in our communities. The NNLM Virtual Symposium: Responding to the COVID-19 Infodemic is an opportunity to address misinformation and mistrust, raise awareness about the pandemic, and efforts to combat it. Symposium attendees can expect to come away from the 2-day experience with a better understanding of COVID-19 and shar...
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Discussion of Systemic Inflammation and its Contribution to Dementia Fisetin Reduces D-Galactose Induced Cognitive Loss in Mice Reprogramming Cancer Cells into Normal Somatic Cells Considering Longevity Medicine and the Education of Physicians Researchers Generate Thyroid Organoids Capable of Restoring Function in Mice In Search of Transcriptional Signatures of Aging A Pace of Aging Biomarker Correlates with Manifestations of Aging Targeting Tissues with Extracellular Vesicles Calorie Restriction Slows Aging of the Gut Microbiome in Mice Mitochondrial DNA Heteroplasmy in the Aging Heart Evidence for Hea...
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This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA dam...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, Desferal, deferoxamine mesylate for injection, which is approved for the treatment of acute iron intoxication and chronic iron overload, was used to explore the beneficial effects on preventing aging-induced bone loss and mitigating dysfunction of aged BMSCs. High-dose Desferal significantly prevented bone loss in aged rats. Compared with controls, the ex vivo experiments showed that short-term Desferal administration could promote the potential of BMSC growth and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs and revise the expression of stemness/se...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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In this study, young adult mice were submitted to endurance exercise training and the function, differentiation, and metabolic characteristics of satellite cells were investigated in vivo and in vitro. We found that injured muscles from endurance-exercised mice display improved regenerative capacity, demonstrated through higher densities of newly formed myofibres compared with controls (evidenced by an increase in embryonic myosin heavy chain expression), as well as lower inflammation (evidenced by quantifying CD68-marked macrophages), and reduced fibrosis. Enhanced myogenic function was accompanied by an increased ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, all NAFLD histological stages were associated with significantly increased overall mortality, and this risk increased progressively with worsening NAFLD histology. Most of this excess mortality was from extrahepatic cancer and cirrhosis, while in contrast, the contributions of cardiovascular disease and HCC were modest. BMP6 as a Target for Pro-Angiogenic Therapies https://www.fightaging.org/archives/2020/10/bmp6-as-a-target-for-pro-angiogenic-therapies/ Today's research materials are focused on the fine details of angiogenesis, the formation of new blood vessels, and point to BMP6 as a po...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Douglas Brooks served as the head of the White House Office of National AIDS Policy during the Obama Administration as the first openly gay, HIV-positive African American to hold the job. He focused on addressing the health needs of those at higher risk of HIV infection, and is now executive director of community engagement at the biopharmaceutical company Gilead Sciences. Dr. Otis Brawley was chief medical and scientific officer of the American Cancer Society before becoming a professor of oncology at Johns Hopkins, where he oversees a research effort exploring disparities in cancer rates and outcomes. Over a Zoom call, t...
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