Almost Every Doctor Recommends Sunscreen. So Why Don ’t We Know More About Its Safety?

Each year, as Memorial Day approaches, Holly Thaggard braces herself for the headlines. About how sunscreen may be damaging coral reefs. About the possible flammability of spray-on sunscreen. Headlines—as there were this year—about how sunscreen contains chemicals that could harm your health. “This has happened every single year for the last decade of my life,” says Thaggard, founder of Texas-based Supergoop, a sunscreen company that brands itself as reef-safe and free of hundreds of potentially problematic ingredients. This year, the is-sunscreen-dangerous news cycle started in May, when Valisure, an independent laboratory dedicated to quality-testing pharmaceuticals and personal-care products, released a report warning that its scientists found benzene—a carcinogen also found in vehicle emissions and cigarette smoke—in 78 U.S. sun-care products. Benzene is not an ingredient in sunscreens, but rather a contaminant likely introduced during the manufacturing process, and experts say it’s not clear whether the amount detected in sunscreens could actually lead to health risks. But in July, Johnson &Johnson voluntarily recalled five of its Neutrogena and Aveeno sunscreen sprays due to the presence of benzene. The company stressed that the recall came from an abundance of caution, and that “the levels detected in our testing would not be expected to cause adverse health consequences,” but it still kicked off a fresh flurry ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthscienceclimate Public Health Source Type: news

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Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer in the pediatric population and represents the second most common malignancy in adolescent females. Historically, PTC has been classified on the basis of histology, however, accumulating data indicate that molecular subtyping based on somatic oncogenic alterations along with gene expression profiling can better predict clinical behavior and may provide opportunities to incorporate oncogene-specific inhibitory therapy to improve the response to radioactive iodine (RAI). In this issue of the JCI, Y.A. Lee, H. Lee, and colleagues showed th...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
BACKGROUND Molecular characterization in pediatric papillary thyroid cancer (PTC), distinct from adult PTC, is important for developing molecularly targeted therapies for progressive radioiodine-refractory (131I-refractory) PTC.METHODS PTC samples from 106 pediatric patients (age range: 4.3–19.8 years; n = 84 girls, n = 22 boys) who were admitted to SNUH (January 1983–March 2020) were available for genomic profiling. Previous transcriptomic data from 125 adult PTC samples were used for comparison.RESULTS We identified genetic drivers in 80 tumors: 31 with fusion oncogenes (RET in 21 patients, ALK in 6 patients,...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Herculean efforts by the Wellcome Sanger Institute, the National Cancer Institute, and the National Human Genome Research Institute to sequence thousands of tumors representing all major cancer types have yielded more than 700 genes that contribute to neoplastic growth when mutated, amplified, or deleted. While some of these genes (now included in the COSMIC Cancer Gene Census) encode proteins previously identified in hypothesis-driven experiments (oncogenic transcription factors, protein kinases, etc.), additional classes of cancer drivers have emerged, perhaps none more surprisingly than RNA-binding proteins (RBPs). Over...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Intratumoral T cells that might otherwise control tumors are often identified in an “exhausted” state, defined by specific epigenetic modifications and upregulation of genes such as CD38, cytotoxic T-lymphocyte–associated protein 4 (CTLA4), and programmed cell death 1 (PD1). Although the term might imply inactivity, there has been little study of this state at the phenotypic level in tumors to understand the extent of their incapacitation. Starting with the observation that T cells move more quickly through mouse tumors the longer they reside there and progress toward exhaustion, we developed a nonstimula...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
BACKGROUND Germline mutations in telomerase and other telomere maintenance genes manifest in the premature aging short telomere syndromes. Myelodysplastic syndromes and acute myeloid leukemia (MDS/AML) account for 75% of associated malignancies, but how these cancers overcome the inherited telomere defect is unknown.METHODS We used ultra-deep targeted sequencing to detect somatic reversion mutations in 17 candidate telomere lengthening genes among controls and patients with short telomere syndromes with and without MDS/AML, and we tested the functional significance of these mutations.RESULTS While no controls carried somat...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
The care sector faces catastrophic staff shortages unless unvaccinated workers get their Covid shot by midnight (Thursday) or the government listens to reason and abandons its draconian ‘no jab, no job’ policy, warns UNISON. Care workers must have their first vaccination today (Thursday) to beat the government’s deadline of 11 November to be double-jabbed or be banned from entering care homes in England. UNISON believes mandatory vaccination should be scrapped or thousands of people may lose out on the support they need. The care sector is already in the grip of a severe staffing crisis and...
Source: UNISON meat hygiene - Category: Food Science Authors: Tags: News Press release adult social care Mandatory vaccination Source Type: news
OBJECTIVES: Sexual trauma poses a significant concern and is associated with heightened stress, negative health repercussions, and adverse economic effects. A history of abuse may increase a woman's risk of developing cancer, in particular cervical cancer....
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
I was looking through ASCO and ACS with regards to any information pertaining to surveillance imaging recommendations for various cancer types after treatment (surgery, radiotherapy, chemotherapy). I understand that factors such as location and cell type or other markers complicate this and therefore each cancer type is unique. I was able to only find a few guideline articles listed as "current" for maybe 4 or 5 frequently diagnosed cancers. I was curious if any single organization or... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Hematology / Oncology Source Type: forums
The 2019-20 burns emitted twice as much CO2 than previously thought and seeded the ocean thousands of kilometers away with nutrients
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
The Maple Grove-based company is using the funds to develop its cancer treatment through FDA 510(k) approval, which will include a clinic study for the management of prostate cancer.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
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