Cytokine responses in non-lesional psoriatic skin as clinical predictor to anti-TNF agents

Capsule summary Enrichment of cytokine signatures in non-lesional psoriatic skin, prior to treatment, exhibits associations with future PASI improvement, and we illustrate the feasibility of integrating cytokine signals with transcriptomic data for drug response prediction in psoriasis.

Source: Journal of Allergy and Clinical Immunology - August 2, 2021 Category: Allergy & Immunology Authors: Lam C. Tsoi, Matthew T. Patrick, Shao Shuai, Mrinal K. Sarkar, Sunyi Chi, Bethany Ruffino, Allison C. Billi, Xianying Xing, Ranjitha Uppala, Cheng Zang, Joseph Fullmer, Zhi He, Emanual Maverakis, Nehal N. Mehta, Bethany E. Perez White, Spiro Getsios, Yola Source Type: research