A Review of the Phytochemistry, Ethnobotany, Toxicology, and Pharmacological Potentials of Crescentia cujete L. (Bignoniaceae)

Evid Based Complement Alternat Med. 2021 Jul 7;2021:6683708. doi: 10.1155/2021/6683708. eCollection 2021.ABSTRACTCrescentia cujete is an economical and medicinal plant of wide indigenous uses including hypertension, diarrhea, respiratory ailments, stomach troubles, infertility problems, cancer, and snakebite. Despite these attributes, C. cujete is largely underutilized, notwithstanding the few progresses made to date. Here, we reviewed the available findings on the ethnobotany, phytochemistry, toxicology, and pharmacology, as well as other economic benefits of the plant. The information on the review was gathered from major scientific databases (Google scholar, Scopus, Science Direct, Web of Science, PubMed, Springer, and BioMed Central) using journals, books, and/or chapters, dissertations, and conference proceedings. The review established the antidiabetic, antioxidant, acaricidal, antibacterial, anti-inflammatory, anthelmintic, antivenom, wound healing, neuroprotection, antiangiogenic, and cytotoxic properties from aqueous and organic (particularly ethanol) aerial parts attributed to several secondary metabolites such as flavonoids, alkaloids, saponins, tannins, phenols, cardiac glycosides, phytosterols, reducing sugar, and volatile oils. Economically, the fruit hard outer shell found applications as musical tools, tobacco pipes, bowls, food containers, and bioethanol production. While most of the current studies on C. cujete are mainly from Asia and South America (Philipp...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Source Type: research

Related Links:

Series Type : Expression profiling by RT-PCROrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by RT-PCR Homo sapiens Source Type: research
ConclusionIpatasertib exhibited rapid absorption and was dose-proportional over a broad dose range. Ipatasertib appeared to be a moderate CYP3A inhibitor when administered at 600  mg and could be administered with or without food in clinical studies.Trail registrationNCT01090960 (registered March 23, 2010); NCT02536391 (registered August 31, 2015).
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
ConclusionOur study did not demonstrate a protective role of vitamin E in decreasing the incidence of CIPN in patients receiving taxane-based chemotherapy. However, the recovery from CIPN was much better as compared to the control arm, which may indicate a role for vitamin E in decreasing the duration and severity of CIPN.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
ConclusionsDietary habits of women became less healthy during the transition from pregnancy to 6  years post-pregnancy. However, results should be interpreted with caution due to the different dietary assessment tools used at the two time points.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we reviewed major human studies on the health risks of radiation exposure and showed that sex-related factors may potentially influence the long-term response to radiation exposure. Available data suggest that long-term radiosensitivity in women is higher than that in men who receive a comparable dose of radiation. The report on the biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences, United States emphasized that women may be at significantly greater risk of suffering and dying from radiation-induced cancer than men exposed to the same dose of radiation....
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Most mainstream doctors believe that polycystic ovary syndrome, PCOS, is a disease. PCOS is, after all, associated with markedly increased risk for type 2 diabetes, hypertension, endometrial cancer, and heart disease, in addition to outward signs that include excessive facial and body hair, tendency to being overweight or obese, irregular menstrual cycles, infertility. A crisis of self esteem commonly and understandably results. Mainstream doctors tell you to not worry because they have plenty of prescription drugs to “treat” it, not to mention various hormones, fertility procedures, and gastric bypass. PCOS is...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates acne facial change facial hair gluten-free grain-free grains Inflammation pcos polycystic ovary testosterone undoctored Weight Loss wheat belly Source Type: blogs
"Everything in moderation" is a common piece of healthy eating advice from slim and sexy celebs, dietitians and other lifestyle gurus. It's a call that's thousands of years old: The ancient Greek poet Hesiod wrote the phrase “moderation is best in all things” in his poem Work and Days, written around 700 BCE, and other philosophers and writers have echoed the maxim ever since.  But just because it’s a saying that has persisted throughout history doesn’t mean it’s right, helpful or useful.  While it sounds like wise advice for anyone who wants a low-key approach to heal...
Source: Science - The Huffington Post - Category: Science Source Type: news
More News: Alternative and Complementary Therapies | Antidoxidants | Bangladesh Health | Brain | Cancer | Cancer & Oncology | Clinical Trials | Complementary Medicine | Conferences | Databases & Libraries | Drugs & Pharmacology | Flavonoids | Fruit | Gastric (Stomach) Cancer | Herbs | Hypertension | India Health | Infertility | Neurology | Neuroscience | Organic | Philippines Health | Reproduction Medicine | Respiratory Medicine | Science | Smokers | Study | Sugar | Toxicology