Factors influencing plasma coproporphyrin-I concentration as biomarker of OATP1B activity in patients with rheumatoid arthritis

In conclusion, the present results suggest that inflammatory cytokines do not have clinically significant effects on OATP1B activity, whereas the effects of genetic polymorphisms and uremic toxins should be considered.PMID:34319605 | DOI:10.1002/cpt.2375

Source: Clinical Pharmacology and Therapeutics - July 28, 2021 Category: Drugs & Pharmacology Authors: Hiroyuki Ono Ryota Tanaka Yosuke Suzuki Ayako Oda Takashi Ozaki Ryosuke Tatsuta Keisuke Maeshima Koji Ishii Keiko Ohno Hirotaka Shibata Hiroki Itoh Source Type: research