Effect of Decompressive Craniectomy on Outcome Following Subarachnoid Hemorrhage in Mice [Basic Sciences]

Conclusions— Performing DC to reduce ICP either during or acutely after SAH resulted in more severe bleeding, a higher incidence of rebleeding, and poorer outcome. Thus, elevated post-hemorrhagic ICP plays an important role in controlling bleeding after SAH and should therefore not be reduced acutely. If DC is considered for treating a patient with SAH, the timing of decompression should take these effects into consideration.
Source: Stroke - Category: Neurology Authors: Tags: Animal models of human disease, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Other Stroke Treatment - Surgical Basic Sciences Source Type: research