La administraci ón de una dosis alta de buprenorfina en la sala de emergencias puede mejorar el resultado del tratamiento del trastorno por consumo de opioides

Un estudio encuentra que el tratamiento es seguro y bien tolerado en personas con trastorno por consumo de opioides que experimentan s íntomas de abstinencia
Source: NIDA News - Category: Addiction Tags: News Release, Health and Medical Professionals, NIDAMED News, Opioids, Relapse Prevention, Treatment, Addiction Science, Buprenorphine Source Type: news

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Notice NOT-MD-22-001 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
On a morning Zoom call, a group of Canadian mothers give their full attention to a young man from the Drug User Liberation Front. At 26, Jeremy Kalicum is the age some of their kids would be if they had not died of accidental overdoses. “We’re just sick of it. We’re sick of our friends dying.”Kalicum’s tone is urgent as he walks the moms through a PowerPoint presentation explaining why the Liberation Front, known as DULF, wants to protest on International Overdose Awareness Day and hand out illicit drugs. These wouldn’t be the kind that killed their sons and daughters, he assures them; t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized feature nationpod photography Source Type: news
CONCLUSIONS: Learning and memory impairment are highly prevalent in persons with OUD starting treatment with either methadone or buprenorphine/naloxone in OTPs. Depression and comorbid substance use are prevalent among these individuals, but neither impact learning or memory. However, depression is associated with neurocognitive impairment in other domains. These findings might allow clinicians to help persons with OUD starting OAT to develop compensatory strategies for learning and memory, while providing adjunctive treatment for depression. Trial Registration NCT, NCT01733693. Registered November 4, 2012, https://clinica...
Source: Addiction Science and Clinical Practice - Category: Addiction Authors: Source Type: research
Cancers, Vol. 13, Pages 5345: Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells Cancers doi: 10.3390/cancers13215345 Authors: Hoi-Hin Kwok Boning Gao Koon-Ho Chan Mary Sau-Man Ip John Dorrance Minna David Chi-Leung Lam Tobacco smoking is the top risk factor for lung cancer development. Nicotine in cigarettes can induce addiction, and its derivatives become potent carcinogens after metabolic activation and activate oncogenic signaling in lung epithelial cells through their expressed nicotinic acetylcholine receptors (nACh...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
AbstractEntering tertiary education is a critical developmental task during emerging adulthood when exploration of life meaning becomes salient. A strong sense of meaning in life (MIL) plays a key role in smooth transition to college. However, little is known about how MIL develops in the first year of college, and even less is studied about the extent to which such development is a function of social relationships and predicts subsequent adjustment outcomes in college freshmen. This three-wave longitudinal research aims to address these underexplored questions, collecting data from Chinese college freshmen regarding their...
Source: Journal of Happiness Studies - Category: Psychiatry & Psychology Source Type: research
AbstractSince stress is known to play a role in the development of physical and mental illness, empirically validated measurements are required to assess the effect of adverse events such as the COVID-19 pandemic. The purpose of this study was to develop and evaluate the psychometric properties of the Adversity and Stress Scale (ASS). A sample of 3937 adults living in Mexico was used. The structure of the instrument was evaluated using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Construct validity was measured through associations between the ASS and psychological symptoms. In the EFA, the rel...
Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
ConclusionThe Risk Perception to COVD-19 Scale (RP-COVID-19-S) showed satisfactory psychometric properties to evaluated risk perception related to COVID-19 in Cuban population sample. Middle level of global risk perception was found in the sample. High level of risk perception about COVID-19 was found on participants older than 42  years old and in woman.
Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
This study aimed to examine the association of cigarette smoking with depression and anxiety in a large sample of formal and contractual employees of a mill steel company, Isfahan, Iran. This cross-sectional study was performed in 2014 among 3063 formal and contractual employees. Multi-stage cluster sampling along with stratified sampling based on managerial sections were employed for participants ’ selection. Data gathering was done by some validated Iranian version of self-administered questionnaires including, International Physical Activity – Short Form, Effort–Reward Imbalance, Hospital Anxiety and D...
Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
The phenomenon of female preponderance in depression has been well-reported, which has been challenged by higher rates of suicide and addictive behaviors in males, and a longer life-span in females. We thus propose an alternative hypothesis “Gender differences in self-reporting symptom of depression,” suggesting mild-moderate depression tends to be reported more often by females, and severe depression and suicide tend to be reported more often by males. Potential mechanisms that account for this difference may include three aspects: covariation between estrogen levels and the incidence peak of female depression...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ConclusionsThese data support the idea that mitragynine could be used as safe medication therapy to treat opiate addiction with beneficial effects on cognitive deficits.
Source: Psychopharmacology - Category: Psychiatry Source Type: research
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