The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma

CONCLUSIONS: The expression of the exosomal markers (CD63 and CD9) increased in patients with rectal adenocarcinoma after treatment with NCCR. The exosomal markers (CD63 and CD9) may have a prognostic significance. There was a trend for higher CD63 and CD9 expression in patients with high NAR score compared with low-intermediate NAR scores. The lack of statistical significance is likely due to the small sample size.PMID:34316329 | PMC:PMC8310674 | DOI:10.18632/oncotarget.28025

Source: Oncotarget - July 28, 2021 Category: Cancer & Oncology Authors: Moh'd Khushman Pranitha Prodduturvar Wadad Mneimneh Valeria Dal Zotto Shalla Akbar Leander Grimm Paul Rider John Hunter Omar Alkharabsheh Girijesh Kumar Patel Jesus C Fabregas Ajay P Singh Source Type: research