IJERPH, Vol. 18, Pages 7996: Association of Short-Term Particulate Matter Exposure among 5-Year Cancer Survivors with Incident Cardiovascular Disease: A Time-Stratified Case-Crossover Study

IJERPH, Vol. 18, Pages 7996: Association of Short-Term Particulate Matter Exposure among 5-Year Cancer Survivors with Incident Cardiovascular Disease: A Time-Stratified Case-Crossover Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph18157996 Authors: Choi Kim Choi Jeong Kim Chang Kim Kim Cho Lee Son Park The association of short-term particulate matter concentration with cardiovascular disease (CVD) among cancer survivors is yet unclear. Using the National Health Insurance Service database from South Korea, the study population consisted of 22,864 5-year cancer survivors with CVD events during the period 2015–2018. Using a time-stratified case-crossover design, each case date (date of incident CVD) was matched with three or four referent dates, resulting in a total of 101,576 case and referent dates. The daily average particulate matter 10 (PM10), 2.5 (PM2.5), and 2.5–10 (PM2.5–10) on the day of case or referent date (lag0), 1–3 days before the case or referent date (lag1, lag2, and lag3), and the mean value 0–3 days before the case or referent date (lag0–3) were determined. Conditional logistic regression was conducted to calculate the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for CVD according to quartiles of PM10, PM2.5, and PM2.5–10. Compared to the 1st (lowest) quartile of lag0–3 PM10, the 4th (highest) quartile of lag0–3 PM10 was associated with hig...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research