Argonaute Autoantibodies as Biomarkers in Autoimmune Neurologic Diseases

Conclusions AGO-Abs might be potential biomarkers of autoimmunity in patients with central and peripheral nonparaneoplastic neurologic diseases. In 7 patients, AGO-Abs were the only biomarkers; thus, their identification may be useful to suspect the autoimmune character of the neurologic disorder. Classification of Evidence This study provides Class III evidence that AGO-Abs are more frequent in patients with autoimmune neurologic diseases than controls.

http://nn.neurology.org/cgi/content/short/8/5/e1032?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - July 28, 2021 Category: Neurology Authors: Do, L.-D., Moritz, C. P., Muniz-Castrillo, S., Pinto, A.-L., Tholance, Y., Brugiere, S., Coute, Y., Stoevesandt, O., Taussig, M. J., Rogemond, V., Vogrig, A., Joubert, B., Ferraud, K., Camdessanche, J.-P., Antoine, J.-C., Honnorat, J. Tags: Autoimmune diseases, Peripheral neuropathy, Paraneoplastic syndrome Article Source Type: research