Differentiation of adult rat mesenchymal stem cells to GABAergic, dopaminergic and cholinergic neurons.

CONCLUSIONS: These new differentiation cocktails should be further investigated and in the next experiment only a part of MSCs that expressed the Cxcr4 receptor will be differentiated. We suppose that the Cxcr4(+) cells may differentiate more easily and as a result, we may achieve a homogenous population of one phenotype of neurons.
PMID: 25712637 [PubMed - in process]

Source: Pharmacological Reports - February 26, 2015 Category: Drugs & Pharmacology Authors: Borkowska P, Fila-Danilow A, Paul-Samojedny M, Kowalczyk M, Hart J, Ryszawy J, Kowalski J Tags: Pharmacol Rep Source Type: research