Gambogic amide selectively upregulates TrkA expression and triggers its activation.

CONCLUSION: This study provides a novel mechanism of how gambogic amide regulates TrkA receptor, other than mimicking NGF in triggering TrkA activation.
PMID: 25712642 [PubMed - in process]

Source: Pharmacological Reports - February 26, 2015 Category: Drugs & Pharmacology Authors: Shen J, Yu Q Tags: Pharmacol Rep Source Type: research