The effects of valproate and olanzapine on the abnormal behavior of diacylglycerol kinase β knockout mice.

CONCLUSION: These results suggest that the abnormal behaviors of DGKβ KO mice is responsive to antimanic drugs, and that DGKβ KO mice are useful as an animal model of mania. PMID: 25712650 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25712650?dopt=Abstract

Source: Pharmacological Reports - February 26, 2015 Category: Drugs & Pharmacology Authors: Ishisaka M, Tsujii S, Mizoguchi T, Tsuruma K, Shimazawa M, Hara H Tags: Pharmacol Rep Source Type: research