The effect of interleukin-35 on the integrity, ICAM-1 expression and apoptosis of human aortic smooth muscle cells.

CONCLUSION: Our data suggest that IL-35 may be an agent affecting the inflammatory properties of AoSMCs and thus it may regulate immune homeostasis of the vascular wall. Hence, IL-35 may be a novel player affecting Ao-SMC-controlled arterial wall immune homeostasis.
PMID: 25712667 [PubMed - in process]

Source: Pharmacological Reports - February 26, 2015 Category: Drugs & Pharmacology Authors: Skowron W, Zemanek K, Wojdan K, Gorzelak P, Borowiec M, Broncel M, Chalubinski M Tags: Pharmacol Rep Source Type: research