Atypical eosinophilic granulomatosis with polyangiitis with spontaneous aspirin reactivity and immunoglobulin E –mediated anaphylaxis

Eosinophilic granulomatosis with polyangiitis (EGPA) and aspirin-exacerbated respiratory disease (AERD) share overlapping pathophysiology characterized by peripheral eosinophilia, nasal polyps, and asthma.1,2 The overlapping nature of the symptoms and etiologies of these 2 diseases emerged recently in a series of case reports reporting additional potential comorbidities.3,4

Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Laurel L. Ball, Stephanie A. Velasquez, Omar M. Al Jammal, Andrew A. White, Praveen Akuthota Tags: Letters Source Type: research