Enhancement of cytotoxicity and induction of apoptosis by cationic nano-liposome formulation of < em > n < /em > -butylidenephthalide in breast cancer cells

In conclusion, BP exhibited an anti-cancer effect on breast cancer cells, and LPPC encapsulation efficiently improved the cytotoxicity of BP via an acceleration of entrapment efficiency to induce cell cycle block and apoptosis. Furthermore, BP/LPPC exhibited a synergistic effect in combination with doxorubicin.PMID:34220320 | PMC:PMC8241786 | DOI:10.7150/ijms.51439
Source: International Journal of Medical Sciences - Category: Biomedical Science Authors: Source Type: research