Efficacy and Safety of Fixed-dose Combination of Etoricoxib/Tramadol vs Acetaminophen/Tramadol for Acute Low Back Pain

Condition:   Acute Low Back Pain Interventions:   Drug: Etoricoxib 90 mg / Tramadol 50 mg;   Drug: Acetaminophen 325 mg / Tramadol 37.5 mg Sponsor:   Laboratorios Silanes S.A. de C.V. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Persons with limb loss and back pain demonstrated opposing coordination strategies between the lower limbs and trunk when vision was removed, perhaps identifying a mechanism for pain recurrence. Vision is the dominant source of balance stabilization in this population, which may increase fall risk when visual feedback is compromised.
Source: Clinical Biomechanics - Category: Orthopaedics Authors: Tags: Original articles Source Type: research
ConclusionPatients with persistent non-specific LBP seem to experience improvement in pain, disability and quality of life years after seeking treatment. However, it remains unclear what factors might have influenced these improvements, and whether they are treatment-related. Studies varied greatly in design, patient population, and methods of data collection. There is still little insight into the long-term natural course of LBP. Additionally, few studies perform repeated measurements during long-term follow-up or report on patient-centered outcomes other than pain or disability.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
CONCLUSIONS: The personal factors "age" and "sex" impact some ICF limitation/restriction categories in cLBP; appropriately addressing these personal features could further improve phase III rehabilitation outcome.Implications for rehabilitationConsistent with calls to explore the age and sex/gender influence on health and disease, little is known how these factors affect the disablement of individuals with chronic back pain.The factors "age" and "sex" drive differences in some categories within the ICF activity/restriction categories.If age- and gender-specific features in activities...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
This study aimed to determine whether exercise using a machine learning-based motion-detecting mobile exercise coaching application (MDMECA) is superior to video streaming-based exercise for improving quality of life and decreasing lower back pain.MATERIALS AND METHODS: The same 14-day daily workout program consisting of five exercises was performed by 104 participants using the MDMECA and another 72 participants using video streaming. The Medical Outcomes Study Short Form 36-Item Health Survey (SF-36) and lower back pain scores were assess as pre- and post-workout measurements. Scores for the treatment-satisfaction subsca...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Source Type: research
AbstractPurposeThe Fremantle back awareness questionnaire (FreBAQ) was recently developed as simple and quick tool to assess back-specific body perception in Low back pain (LBP) patients. The aim of the present study was to translate and cross-culturally adapt the Fremantle back awareness questionnaire (FreBAQ) into a Simplified Chinese version (FreBAQ-C), and evaluate the reliability and validity of the FreBAQ-C in patients with non-specific Chronic Low back pain (CLBP).MethodsThe FreBAQ was translated into Chinese according to established methods. Internal consistency was assessed according to Cronbach ’s alpha. Te...
Source: European Spine Journal - Category: Orthopaedics Source Type: research
ConclusionsInjured PLC and EPI type III were independent risk factors for ADD in patients with traumatic thoracic or lumbar fracture. For such patients without risk factors for ADD, the non-intervertebral fusion should be given a priority if surgery is necessary.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
CONCLUSION: DMCE is effective in improving motor control in the lumbar region and hip joints, thereby ameliorating low back pain in SOWs.PMID:35036258 | PMC:PMC8752866 | DOI:10.1298/ptr.E10121
Source: Health Physics - Category: Physics Authors: Source Type: research
We describe a 57-year-old man with post-polio syndrome and low back pain following a fall at the end of February 2020. The pain, disability and lack of functionality caused by both processes led him to contact a physiotherapy service. A therapeutic planning was carried out for 3 months, where a biobehavioural approach based on therapeutic exercise and education, with an assessment and three face-to-face sessions which were complemented by online follow-up and finalised due to the Sars-Cov-2 pandemic in a telerehabilitation approach. It was organised in two phases; the initial phase lasted 2 weeks with the aim of reducing t...
Source: Physical Therapy - Category: Physiotherapy Authors: Source Type: research
CONCLUSION: DMCE is effective in improving motor control in the lumbar region and hip joints, thereby ameliorating low back pain in SOWs.PMID:35036258 | PMC:PMC8752866 | DOI:10.1298/ptr.E10121
Source: Physical Therapy - Category: Physiotherapy Authors: Source Type: research
Curr Drug Targets. 2022 Jan 14. doi: 10.2174/1389450123666220114151654. Online ahead of print.ABSTRACTIntervertebral disc (IVD) degeneration is a leading cause of lower back pain. Although the etiology of IVD degeneration (IVDD) is unclear, excessive oxidative stress, inflammation and apoptosis and disruption of autophagy play important role in the pathogenesis of IVDD. Therefore, finding a solution to mitigate these processes could stop or reduce the development of IVDD. Melatonin, a powerful antioxidant, plays an important role in regulating cartilage tissue hemostasis. Melatonin inhibits destruction of extracellular mat...
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Source Type: research
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