< em > C < /em > -Methylenation of anilines and indoles with CO < sub > 2 < /sub > and hydrosilane using a pentanuclear zinc complex catalyst

Chem Commun (Camb). 2021 Jul 24. doi: 10.1039/d1cc03675k. Online ahead of print.ABSTRACTThe one-step C-methylenation of anilines and indoles with CO2 and phenylsilane was catalyzed by a pentanuclear ZnII complex to give diarylmethanes via geminal C-H and C-C bond formation. It is proposed that the zinc-hydride complex generated in situ is a catalytically active species and that bis(silyl)acetal is a key intermediate. When aniline was used as a substrate, both the C-methylenation and N-methylation proceeded.PMID:34302161 | DOI:10.1039/d1cc03675k

Source: Chemical Communications - July 24, 2021 Category: Chemistry Authors: Kazuto Takaishi Hiroyasu Kosugi Ritsuki Nishimura Yuya Yamada Tadashi Ema Source Type: research