Identification of serum microRNAs with differential expression between dogs with splenic masses and healthy dogs with histologically normal spleens

CONCLUSIONS AND CLINICAL RELEVANCE: 5 circulating miRNAs were identified that distinguished dogs with splenic hemangiosarcoma or hematoma from those with histologically normal spleens. These 5 miRNAs had higher expression in dogs with splenic masses, indicating upregulation of these circulating miRNAs occurs in these splenic disease states. These miRNAs may be useful as a noninvasive screening tool that uses serum to identify dogs with splenic masses.PMID:34296940 | DOI:10.2460/ajvr.82.8.659
Source: American Journal of Veterinary Research - Category: Veterinary Research Authors: Source Type: research