Retrograde ejaculation following anterior lumbar surgery: a systematic review and pooled analysis

CONCLUSIONS: In a pooled analysis of currently published data on men undergoing first-time open anterior lumbar surgery, this study found an overall incidence of RE of 2.3%. Nearly half of these patients recovered, reporting resolution of symptoms anywhere between 3 months and 48 months. Analysis of risk factors was limited by a paucity of published literature segregating data by sex. However, there was an increased risk associated with rhBMP-2 only when including data collected prior to the FDA warning on its detrimental properties. The authors therefore posit that the risk of RE is probably overestimated in the literature, given that the vast majority of the data available were collected prior to this warning and given the subsequent implementation of precautions when handling rhBMP-2.PMID:34271542 | DOI:10.3171/2020.12.SPINE201101
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Source Type: research