Sequential C-H activation enabled expedient delivery of polyfunctional arenes

Chem Commun (Camb). 2021 Jul 23. doi: 10.1039/d1cc03243g. Online ahead of print.ABSTRACTModular construction of polyfunctional arenes from abundant feedstocks stands as an unremitting pursue in synthetic chemistry, accelerating the discovery of drugs and materials. Herein, using the multiple C-H activation strategy with versatile imidate esters, the expedient delivery of molecular libraries of densely functionalized sulfur-containing arenes was achieved, which enabled the concise construction of biologically active molecules, such as Bipenamol.PMID:34296709 | DOI:10.1039/d1cc03243g

Source: Chemical Communications - July 23, 2021 Category: Chemistry Authors: Wensen Ouyang Xiaoqing Cai Xiaojian Chen Jie Wang Jianhang Rao Yang Gao Yanping Huo Qian Chen Xianwei Li Source Type: research