Characterization of a functional V < sub > 1B < /sub > vasopressin receptor in the male rat kidney, evidence for crosstalk between V < sub > 1B < /sub > and V < sub > 2 < /sub > receptor signaling pathways

This study brings new data on the localization and signaling pathways of V1B-R in the kidney, highlights a crosstalk between V1B-R and V2-R in IMCD and suggests that V1B-R may counterbalance in some pathophysiological conditions the antidiuretic effect triggered by V2-R activation.PMID:34282956 | DOI:10.1152/ajprenal.00081.2021

Source: Am J Physiol Renal P... - July 20, 2021 Category: Urology & Nephrology Authors: Annette Hus-Citharel Nadine Bouby Ma ïthé Corbani Julie Mion Christiane Mendre Judit Darusi Csaba Tomboly Miguel Trueba Claudine Serradeil-Le Gal Catherine Llorens-Cortes Gilles Guillon Source Type: research