Urinary exosomal circular RNAs of sex chromosome origin are associated with gender-related risk differences of clinicopathological features in patients with IgA nephropathy

CONCLUSION: Compared with female patients, males with IgAN had more severe renal dysfunction and a higher probability of glomerular crescent formation. Urine exosomal circRNA chrY:15478147-15481229- might participate in the pathogenesis of IgAN in male patients by altering UTY expressions.PMID:34292531 | DOI:10.1007/s40620-021-01118-7

Source: Journal of Nephrology - July 22, 2021 Category: Urology & Nephrology Authors: Rumei Luan Geng Tian Hong Zhang Xiaolei Shi Jicui Li Rui Zhang Xuehong Lu Source Type: research