TGF- β regulates nerve growth factor expression in a mouse intervertebral disc injury model

Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LB...

Source: BMC Musculoskeletal Disorders - July 23, 2021 Category: Orthopaedics Authors: Yuji Yokozeki, Kentaro Uchida, Ayumu Kawakubo, Mitsufumi Nakawaki, Tadashi Okubo, Masayuki Miyagi, Gen Inoue, Makoto Itakura, Hiroyuki Sekiguchi and Masashi Takaso Tags: Research Source Type: research