High-Tech Exoskeletons Improve Bowel Function in People With Spinal Cord Injury

FRIDAY, July 23, 2021 -- Digestive issues are common after spinal cord injury and can lead to chronic constipation and incontinence. But robotic exoskeleton-assisted walking can improve matters in people with such injuries, researchers say. In an...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Contributors : Hsu-Wen Tseng ; Irina Kulina ; Gethin Thomas ; Lawrie Wheeler ; Jean-Pierre LevesqueSeries Type : Expression profiling by arrayOrganism : Mus musculusTo better understand which genes/pathways are activated in injured muscles following a spinal cord injury (SCI) and how these promote the development of neurogenic heterotopic ossification (NHO), we performed gene expression profiling by microarray of muscles in the early phase following muscle injury.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
This study explores effect of Methylprednisolone (MP) in temporal change of gene expression to look for candidate genes that have potential to develop effective treatment.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Rattus norvegicus Source Type: research
Fecal microbiota transplantation (FMT) is considered an effective treatment for slow transit constipation (STC); nevertheless, the mechanism remains unclear.
Source: Journal of Translational Medicine - Category: Research Authors: Tags: Research Source Type: research
Photo credit Drew Beamer Millions of people consume alcohol, but each person has their own unique relationship with this substance. While many are able to drink in moderation without it negatively impacting their health, relationships, and careers, alcohol use can become problematic for some individuals. Alcohol has a particularly strong impact on seniors, even when consumed infrequently. Age-related changes in the body, chronic health conditions, prescription medications, and other factors can magnify the effects of alcohol consumption... Continue reading on Agingcare for insight into older adults and alcohol use: Minding...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Conclusion: Given the low level of evidence and paucity of data on dietary management of neurogenic bowel, the efficacy of dietary strategies (alone or in combination with others) in managing neurogenic bowel cannot be substantiated from the studies identified. Therefore, more robust studies are warranted to bridge this gap. IMPLICATIONS FOR REHABILITATION Consumption of ∼15 g dietary fibre is shown to be beneficial in managing neurogenic bowel in SCI. Further research is required to strengthen evidence for fibre recommendations and investigating the potential benefits of traditional and non-traditional dietary ...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
Conclusion Recent advances in research on HTLV-1 provide better understanding of the molecular pathogenesis and mechanisms of HAM/TSP, and several clinical trials of novel therapies for patients with HAM/TSP have been initiated. However, long-term improvement of motor disability and quality of life still have not been achieved in HAM/TSP patients, and the clinical management remains challenging. Given that HAM/TSP is characterized by activated T-cells in both the periphery and CNS, studies in HAM/TSP will be highly informative for clarifying the pathogenesis of other neuroinflammatory disorders such as multiple sclerosis....
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract STUDY DESIGN: Prospective cohort study OBJECTIVES: We hypothesized that anti-muscarinic agents alter rectal compliance in SCI patients and that altered rectal compliance relates to bowel symptomatology. Our primary aim was to compare rectal compliance before and after the institution of anti-muscarinics (solifenacin and tolterodine) and an adrenoceptor agonist (mirabegron) in these patients. Additionally, we wanted to evaluate if anorectal manometry differed before and after use of anti-muscarinic agents. SETTING: Tertiary neurogastroenterology clinic, London METHODS: Thirty-five patients with suprac...
Source: Anal Sci - Category: Chemistry Authors: Tags: Spinal Cord Source Type: research
Abstract AimsTo study the effect of quantitative assessment‐based nursing intervention on the bowel function and life quality in patients with neurogenic bowel dysfunction after spinal cord injury. BackgroundNeurogenic bowel dysfunction after spinal cord injury was clinically manifested by abdominal distension, intractable constipation, prolonged defecation and fecal incontinence, which seriously affected the normal life of patients. Traditional ways of nursing for these patients focused on basic care, but lacked sufficient recognition of disease severity and individual needs. Design184 patients with neurogenic bowel dys...
Source: Journal of Clinical Nursing - Category: Nursing Authors: Tags: Original Article Source Type: research
Purpose of review: Pelvic floor disorders (PFDs) can present with gastrointestinal complaints in the adolescent patient, and identification of PFDs is aided by clues in the history and physical examination apparent to the knowledgeable clinician. The aim of this article is to provide a framework for the diagnostic evaluation of the adolescent patient with a PFD and introduce management strategies. Recent findings: Patients with PFDs can present with gastrointestinal symptoms, including abdominal pain, constipation, incomplete evacuation, and fecal incontinence or nongastrointestinal complaints around genitourinary symptom...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ADOLESCENT MEDICINE: Edited by Sara Forman and Sarah Pitts Source Type: research
Conclusion Doctors often assure parents that vaccines are safe, using phrases like “one in a million” and “rare” to describe adverse reactions. Yet, with sad stories like RD’s, thousands of adverse events reported to VAERS, and the creation of a special court for vaccine injuries, informed parents know those vaccine safety claims are simply not true. If you have not already done so, please consider the overall safety of vaccinations. A federal program has awarded billions of dollars, through an arduous, emotionally painful process, to people whose family members have suffered injury or death a...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Case Reports on Vaccine Injury Human Missy Fluegge Patricia Finn transverse myelitis truth about vaccines United States Court of Federal Claims Vaccine Court VAERS Varicella vaccine Source Type: blogs
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