American Society for Colposcopy and Cervical Pathology discusses updated American Cancer Society guidelines on cervical cancer screening

(Wolters Kluwer Health) Last year, the American Cancer Society (ACS) issued an updated set of guidelines for cervical cancer screening - emphasizing the shift toward screening with primary human papillomavirus (HPV) testing. While the ACS recommendation accounts for a transition period to implement primary HPV screening, additional factors should be considered to operationalize these guidelines, according to a special white paper in the July issue of the Journal of Lower Genital Tract Disease (JLGTD), official journal of ASCCP. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Histol Histopathol. 2021 Nov 9:18394. doi: 10.14670/HH-18-394. Online ahead of print.ABSTRACTOBJECTIVE: To screen out high-risk groups of endocervical lesions, explore the effect of length of excision on margin status in women with abnormal endocervical curettage (ECC) and explore the role of ECC in the additional detection of high-grade squamous intraepithelial lesion or worse (HSIL+) under colposcopy and lesion-targeted biopsies.METHODS: The study included 936 patients who underwent loop electrosurgical excision procedure (LEEP) for cervical lesions which were diagnosed by cervical biopsy and ECC at the cervical clinic o...
Source: Histology and Histopathology - Category: Cytology Authors: Source Type: research
CONCLUSION: Primary HPV screening with HPV16/18 partial genotyping is a promising strategy to identify women at current/future risk of>CIN2 in Japan without over-referral to colposcopy.TRIAL REGISTRATION: Trial Registration: UMIN Clinical Trials Registry Identifier: UMIN000013203.PMID:34708593 | PMC:PMC8550923 | DOI:10.3802/jgo.2021.32.e86
Source: Journal of Gynecologic Oncology - Category: OBGYN Authors: Source Type: research
Matthias Jentschke High-risk human papillomavirus (hr-HPV) infection of the cervicovaginal tract is known to be the major cause of cervical cancer. Similar to various other countries, Germany introduced an organized combined screening including cytology and HPV testing in 2020. The participation rate was around 70% in the past. Self-testing for hr-HPV infections could be an option to increase the participation rate. Two dry vaginal self-sampling devices and a device for the self-collection of first-void urine were evaluated in combination with a PCR-based hr-HPV test regarding their clinical performance (sensitivity f...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Conclusions Most findings were HR-HPV positive with negative cytology, which studies suggest may confer low risk of progression in older individuals. In addition, no patient was found to develop cervical malignancy. Despite controversy regarding this recommendation, our data suggest screening cessation may be appropriate with adequate negative screening history.
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Screening HPV Associated Disease Source Type: research
IJERPH, Vol. 18, Pages 10050: Human Papillomavirus (HPV) Self-Sampling among Never-and Under-Screened Indigenous Māori, Pacific and Asian Women in Aotearoa New Zealand: A Feasibility Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph181910050 Authors: Collette Bromhead Helen Wihongi Susan M. Sherman Sue Crengle Jane Grant Georgina Martin Anna Maxwell Georgina McPherson ‘Aivi Puloka Susan Reid Nina Scott Karen Bartholomew In Aotearoa, New Zealand, the majority of cervical cancer cases occur in women who have never been screened or are under-screen...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionWe conclude that both urine and vaginal self-sampling are well accepted by women, with a preference for urine sampling. Although the large majority of women are confident in their ability to perform self-sampling, four to five over ten women preferred specimen collection by a clinician.Trial registrationThe study VALHUDES was registered inClinicalTrials.gov (identifier:NCT03064087).
Source: Archives of Public Health - Category: International Medicine & Public Health Source Type: research
Oncol Lett. 2021 Sep;22(3):684. doi: 10.3892/ol.2021.12945. Epub 2021 Jul 27.ABSTRACTThe present study aimed to identify the factors that independently contribute to disease recurrence among women first-time treated for high-grade cervical intraepithelial neoplasia (CIN) during 4-6 years of follow-up. Overall, 529 of 530 eligible patients participated; these patients all attended a 1st follow-up appointment ~6 months post-conization, at which time high-risk human-papillomavirus (HPV) testing, liquid-based cytology and colposcopy were performed. Full data on margin excision status, other aspects of initial treatment and com...
Source: Oncology Letters - Category: Cancer & Oncology Authors: Source Type: research
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