Comparison of effect of intraperitoneal instillation of additional dexmedetomidine or clonidine along with bupivacaine for post-operative analgesia following laparoscopic cholecystectomy

Conclusion: The addition of alpha-2 agonists to bupivacaine reduces the post-operative opioid consumption, and dexmedetomidine appears to be superior to clonidine in prolonging time to first analgesic request.

Source: Indian Journal of Anaesthesia - July 23, 2021 Category: Anesthesiology Authors: Thottikat Kaarthika Sri Devi Radhapuram Aloka Samantaray Hemalatha Pasupuleti Mangu Hanumantha Rao R Bharatram Source Type: research