Functional analysis of pde gene and its role in the pathogenesis of Xanthomonas oryzae pv. oryzicola

In this study, the function of EAL domain protein encoded by pde (FE36_09715) gene in the regulation of c-di-GMP was investigated. Results of this study, showed that the deletion of pde gene led to a significant reduction in the virulence of Xoc and was positively related to the reduction of extracellular polysaccharides production, biofilm formation, and flagellar motility. However, these significantly impaired properties from the ∆pde mutant strain were partially recovered in the complementary strain. In addition, the deletion of pde gene in Xoc strain YM15had no visible effect on the colony morphology, amylase, and protease activities. It is concluded that, as a regulator for the c-di-GMP level, the pde gene plays an important role in partial biological processes in Xoc and is essential for its virulence.PMID:34284137 | DOI:10.1016/j.meegid.2021.105008

Source: Infection, Genetics and Evolution - July 20, 2021 Category: Genetics & Stem Cells Authors: Xiaoyan Wan Jun Yang Waqar Ahmed Qi Liu Yanfang Wang Lanfang Wei Guanghai Ji Source Type: research