Evaluation of the usefulness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a context with increased resistance of Plasmodium falciparum in Kingasani Hospital, Kinshasa in the Democratic Republic of Congo

CONCLUSION: IPTp-SP was not associated with reduced maternal malaria in our study, but evidence was found of a prophylactic effect against adverse pregnancy outcomes. To counteract further loss of clinical effects of IPTp-SP in the study population, alternative strategies able to improve its anti-malarial efficacy such as combination of SP with partner molecules should be implemented.PMID:34284138 | DOI:10.1016/j.meegid.2021.105009

Source: Infection, Genetics and Evolution - July 20, 2021 Category: Genetics & Stem Cells Authors: Nadine Kayiba Kalenda Doudou Malekita Yobi Vanessa Rodanis Tchakounang Kouoneyou Dieudonn é Makaba Mvumbi Pius Zakayi Kabututu Brecht Devleesschauwer Erick Mukomena Sompwe Patrick DeMol Marie-Pierre Hayette Georges Lelo Mvumbi Angel Rosas-Aguirre Paul Lu Source Type: research