Characterization of interstitial infiltrates in MPO and PR3 anti-neutrophil cytoplasmic antibody glomerulonephritis

CONCLUSION: These data confirm the role of T cells in ANCA GN and demonstrate no differences in interstitial T and B cell infiltrates between PR3 and MPO ANCA GN. Higher FOXP3 signal associates with lower renal function, suggesting a role for regulatory T cells. Further characterization of this T cell subset should be explored in future studies.PMID:34283405 | DOI:10.1007/s40620-021-01126-7
Source: Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research