Mechanotaxis directs Pseudomonas aeruginosa twitching motility [Biophysics and Computational Biology]
The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellular filaments called type IV pili (T4P). Single cells twitch by sequential T4P extension, attachment, and retraction. How single cells coordinate T4P to efficiently navigate surfaces remains unclear. We demonstrate that P. aeruginosa actively directs twitching in...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Marco J. Kuhn, Lorenzo Tala, Yuki F. Inclan, Ramiro Patino, Xavier Pierrat, Iscia Vos, Zainebe Al–Mayyah, Henriette Macmillan, Jose Negrete Jr, Joanne N. Engel, Alexandre Persat Tags: Biophysics and Computational Biology, Microbiology Biological Sciences Source Type: research