Preterm birth etiological pathways: a Bayesian networks and mediation analysis approach

CONCLUSION: The identified pathways suggest PTB etiological lines related to social disparities and exposure to genitourinary tract infections.IMPACT: Few prenatal visits (<5) and vaginal bleeding are two of the main predictors for spontaneous preterm birth in the studied population. Few prenatal visits mediates part of the risk associated with maternal age less than 20 years and vaginal bleeding in the second trimester mediates part of the risk associated with vaginal bleeding in the first trimester and with urinary tract infection. Social disparities and exposure to genitourinary tract infections would be etiological lines of spontaneous preterm birth.PMID:34282276 | DOI:10.1038/s41390-021-01659-4

Source: Pediatric Research - July 20, 2021 Category: Pediatrics Authors: Dario Elias Hebe Campa ña Fernando A Poletta Silvina L Heisecke Juan A Gili Julia Ratowiecki Mariela Pawluk Maria R Santos Viviana Cosentino Rocio Uranga Cesar Saleme Monica Rittler Hugo B Krupitzki Jorge S Lopez Camelo Lucas G Gimenez Source Type: research