Anti-arrhythmic Drugs —a Review and Comment on Relevance in the Current Era: Part 1

AbstractPurpose of reviewThere is apprehension and a general lack of familiarity with regard to using the ionic channel specific anti-arrhythmic agents among internists and even general cardiologists.Recent findingsThis may be related to their relative infrequent use, complicated mechanisms of actions, and real or perceived risks involved with their use. For example, the fact that coronary artery disease is listed as contraindication to the prescription of class IC agents, when so many patients are noted to have presence of non-obstructive disease on increasingly done CT scans, causes confusion and uncertainty about their use.SummaryThis review paper will attempt to lay out the general pharmacology of the commonly used anti-arrhythmic drugs and discuss their relevance and safe use in current clinical medicine.
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research