Melphalan as a Promising Treatment for BRCA-Related Ovarian Carcinoma

ConclusionsOur study represents the largest cohort of heavily-pretreated EOC patients receiving melphalan treatment. Here, we report a considerable clinical activity of melphalan chemotherapy, more evident in a subset of BRCA1/2 mutated patients. Prospective studies to validate these findings are warranted.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research