Lifting Weights? Your Fat Cells Would Like to Have a Word

A cellular chat after your workout may explain in part why weight training burns fat.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Exercise Muscles Obesity Mice Research Weight Lifting FASEB Journal Source Type: news

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You can say one thing for Professor Mark Haub: He knows how to make a lesson stick. Haub, who teaches nutrition at Kansas State University, wanted to prove to his students that weight loss is simply about calories. So, for 10 weeks, the professor proceeded to eat an 1,800-calorie diet consisting of a Twinkie every three hours. He also dined on Doritos, Little Debbies, sugary cereal and other junk food. When he started, Haub tipped the scales at 201 pounds, which for his height was considered overweight. By the end of his snack-food spree, he had lost 27 pounds, putting him at a svelte 174. The story went viral, with the me...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: news
This article is categorized under: Metabolic Diseases> Molecular and Cellular Physiology
Source: Wiley Interdisciplinary Reviews: Systems Biology and Medicine - Category: Biomedical Science Authors: Tags: Overview Source Type: research
In conclusion, adiposity levels of children and adolescents with a genetic predisposition to obesity might be modified by improving CRF and muscular strength.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
This article is categorized under: Metabolic Diseases> Molecular and Cellular Physiology
Source: Wiley Interdisciplinary Reviews: Systems Biology and Medicine - Category: Biomedical Science Authors: Tags: Overview Source Type: research
How could that change our understanding about, for starters, chronic disease, aging and obesity?
Source: NYT Health - Category: Consumer Health News Authors: Tags: Calories Research Diet and Nutrition Source Type: news
In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Curr Biol. 2021 Aug 26:S0960-9822(21)01120-9. doi: 10.1016/j.cub.2021.08.016. Online ahead of print.ABSTRACTUnderstanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1-3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response-energy compensat...
Source: Current Biology - Category: Biology Authors: Source Type: research
In this study, we further determined its role in natural aging related metabolic disorders. The results demonstrated that aged CD47 deficient mice (under normal chow diet) had reduced body weight and fat mass, and improved glucose tolerance as compared to aged wild type (WT) mice. Indirect calorimetry result showed that food intake and total activity were comparable between two genotypes. However, CD47 deficient mice had increased energy expenditure and better cold tolerance, accompanied by increased white adipose tissue browning and well-maintained juvenile morphology of brown adipose tissue (BAT). Moreover, transcriptome...
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Source Type: research
Curr Biol. 2021 Aug 26:S0960-9822(21)01120-9. doi: 10.1016/j.cub.2021.08.016. Online ahead of print.ABSTRACTUnderstanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1-3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response-energy compensat...
Source: Current Biology - Category: Biology Authors: Source Type: research
In this study, we further determined its role in natural aging related metabolic disorders. The results demonstrated that aged CD47 deficient mice (under normal chow diet) had reduced body weight and fat mass, and improved glucose tolerance as compared to aged wild type (WT) mice. Indirect calorimetry result showed that food intake and total activity were comparable between two genotypes. However, CD47 deficient mice had increased energy expenditure and better cold tolerance, accompanied by increased white adipose tissue browning and well-maintained juvenile morphology of brown adipose tissue (BAT). Moreover, transcriptome...
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Source Type: research
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