Prostate hypofractionated radiotherapy (62Gy at 3.1Gy per fraction) with injection of hyaluronic acid: final results of the RPAH1 study

CONCLUSION: Despite the inefficacy of HA injection was not rejected, we observed the absence of Grade 3 or 4 rectal toxicity as well as a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up. Late urinary toxicities are the most frequent but the rate decreases largely at 3 years.ADVANCES IN KNOWLEDGE: With an injection of HA, hypofractionated irradiation in 4 weeks is well tolerated with no Grade 3 or 4 GI toxicity and a rate of Grade 2 rectal bleeding below 10% at 36 months of follow-up.PMID:34282946 | DOI:10.1259/bjr.20210242

Source: The British Journal of Radiology - July 20, 2021 Category: Radiology Authors: Olivier Chapet Corina Udrescu Sylvie Bin Evelyne Decullier Pascal Fenoglietto Amandine Beneux Bruno Segui Ciprian Enachescu Sonya Gaudioz Alain Ruffion David Azria Source Type: research