Genes, Vol. 12, Pages 1103: Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes

In conclusion, through a comprehensive multi-omics approach towards our HGSOC cohorts, two distinctive types of HGSOC (HRR-activated and mesenchymal) were identified. Our novel EMT index seems to be a potential prognostic biomarker for HGSOC.

Source: Genes - July 20, 2021 Category: Genetics & Stem Cells Authors: Min-Hwan Sohn Se Ik Kim Jong-Yeon Shin Hee Seung Kim Hyun Hoon Chung Jae-Weon Kim Maria Lee Jeong-Sun Seo Tags: Article Source Type: research