Effect of locally delivered adjunctive antibiotics during surgical periodontal therapy: a systematic review and meta-analysis

ConclusionWithin the current review ’s limitations, locally delivered antibiotics during surgical periodontal therapy results in post-surgical improvements for CAL, PPD, and BOP (≤6 months) with a longer-lasting GI improvement. Further randomized controlled trials are needed with true periodontal end-points to assess the ideal ant ibiotic agent, dosage, and delivery methods.Clinical relevanceLocal delivery of antibiotics during periodontal surgery improved clinical parameters for up to 6-month follow-up, with beneficial longer effects on gingival inflammation. Within the current study ’s limitation, the presented evidence could support the elective usage of locally delivered antibiotics during surgical periodontal therapy.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research