Viruses, Vol. 13, Pages 1401: Laboratory Findings in Patients with Probable Dengue Diagnosis from an Endemic Area in Colombia in 2018

Viruses, Vol. 13, Pages 1401: Laboratory Findings in Patients with Probable Dengue Diagnosis from an Endemic Area in Colombia in 2018 Viruses doi: 10.3390/v13071401 Authors: Jenny C. Cardenas Sandra Y. Giraldo-Parra Maria U. Gonzalez Lady Y. Gutierrez-Silva Lucy Jaimes-Villamizar Alba L. Roa-Parra Daisy J. Carvajal Hugo O. Valdivia Juan F. Sanchez Tonya M. Colpitts Berlin Londono-Renteria As demonstrated with the novel coronavirus pandemic, rapid and accurate diagnosis is key to determine the clinical characteristic of a disease and to improve vaccine development. Once the infected person is identified, hematological findings may be used to predict disease outcome and offer the correct treatment. Rapid and accurate diagnosis and clinical parameters are pivotal to track infections during clinical trials and set protection status. This is also applicable for re-emerging diseases like dengue fever, which causes outbreaks in Asia and Latin America every 4 to 5 years. Some areas in the US are also endemic for the transmission of dengue virus (DENV), the causal agent of dengue fever. However, significant number of DENV infections in rural areas are diagnosed solely by clinical and hematological findings because of the lack of availability of ELISA or PCR-based tests or the infrastructure to implement them in the near future. Rapid diagnostic tests (RDT) are a less sensitive, yet they represent a timely way of detecting DENV infections. The purpose of thi...
Source: Viruses - Category: Virology Authors: Tags: Communication Source Type: research