Correlation of body mass index to Ghrelin and IGF-1 among Egyptian children with short stature

CONCLUSION: There was a negative feedback loop between ghrelin and IGF-1, whereas a positive feedback between ghrelin and BMI. BMI was more affected in the ISS group but was non-significantly correlated with ghrelin. There was no significant compensatory response of ghrelin suggesting its contribution to the pathogenesis of ISS.PMID:34273273 | DOI:10.1016/j.jped.2021.04.012
Source: Jornal de Pediatria - Category: Pediatrics Authors: Source Type: research