The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation

CONCLUSIONS: TRYCATs levels were related to specific clinical and biological features, such as atypical symptoms or a proinflammatory status. Modulation of KP may potentially benefit a specific subset of depressed patients. Clinical studies should focus on patients with clear evidence of KP dysregulations.PMID:34252568 | DOI:10.1016/j.bbi.2021.07.007

Source: Brain, Behavior, and Immunity - July 12, 2021 Category: Neurology Authors: Yuri Milaneschi Kelly A Allers Aartjan T F Beekman Erik J Giltay Sascha Keller Robert A Schoevers Sigurd D S üssmuth Heiko G Niessen Brenda W J H Penninx Source Type: research