Clinical trials: Renal safety of TDF as pre-exposure prophylaxis for HIV-1 infection

Nature Reviews Nephrology 11, 127 (2015). doi:10.1038/nrneph.2015.1 Author: Ellen F. Carney Use of tenofovir disoproxil fumarate (TDF) as an antiretroviral therapy is associated with declines in estimated glomerular filtration rate (eGFR) in patients with HIV-1 infection. TDF is also used as a pre-exposure prophylaxis (PrEP) in adults at risk of HIV-1 infection, but limited data are
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research